VAN NUYS (CBSLA) — Several people were hospitalized in a suspected DUI crash in Van Nuys.

A car and an SUV were involved in a head-on crash on Victory Boulevard at Kester Avenue just before 5 a.m. Wednesday. At least three people have been taken to hospitals with major injuries.

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One of the people taken to the hospital was the driver of a white SUV. Police say she will be treated for her injuries, then arrested on suspicion of DUI.

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The gray car’s engine compartment was smashed in and left in the middle of Victory Boulevard, surrounded by a large debris field. The white SUV, which apparently ricocheted onto the sidewalk in front of an apartment building, its engine compartment also smashed in.

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Crews worked to clear the scene and reopen the roadway before the morning rush hour.