DOWNTOWN LOS ANGELES (CBSLA.com) — Two people remained hospitalized Monday for treatment of injuries sustained in a multi-vehicle crash that took place in downtown Los Angeles.

Two vehicles and a delivery truck carrying carbon dioxide collided shortly after 3:30 a.m. in the 1500 block of South Central Avenue near 16th Street, according to the Los Angeles Fire Department.

The impact of the multi-vehicle crash caused at least one of the vehicles to erupt in flames.

Upon their arrival, firefighters freed one person who became trapped inside the car.

Paramedics transported the victim to a hospital in critical condition.

The 61-year-old driver of the truck was also transported to a hospital in fair condition for treatment of back pain.

No other injuries were reported.

A preliminary investigation revealed a wrong-way driver traveling at 70 miles per hour barreled into the truck.

According to firefighters, the car fire spread to an adjacent two-story commercial building, however, flames did not spread inside the structure.

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