NEWPORT BEACH (CBSLA.com) — Six people have been injured, at least one seriously, in a head-on collision in Orange County.

READ MORE: Dodgers Set To Open NLCS Against Braves

The two-car crash happened about 11:30 p.m. Saturday.

Investigators say one car collided with a second vehicle as it transitioned from the Pacific Coast Highway to Newport Boulevard.

READ MORE: Water Main Break Forces Road Closure In Marina Del Rey

Police say one person was taken to an area hospital in serious condition while three others had minor injuries.

The injuries of the other two people have not been released.

MORE NEWS: Multiple Victims Wounded In Whittier Shootings During Vigil

The cause of the crash remains under investigation.