SAN DIEGO (AP) — It’s not just a random mutant spider bite that sets Hollywood’s new Peter Parker on the superhero career track.

From the trailer of “The Amazing Spider-Man” and footage previewed Friday at the Comic-Con fan convention, it’s clear that something dark and deep is at the heart of Peter’s fateful encounter with that spider. He may even be a Spider-Man of destiny.

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The footage offers glimpses of the orphan boy’s natural father (Campbell Scott), a man shrouded in a mystery that Peter (Andrew Garfield) needs to unravel as a youth.

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Garfield, co-star Emma Stone and director Marc Webb would not divulge details, but they did acknowledge that a personal quest puts Peter on a collision course with the spider whose bite imparts superpowers.

“The Amazing Spider-Man” hits theaters in July 2012.

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