LOS ANGELES (CBS) — Charlie Sheen’s longtime publicist has called it quits.

In a statement released Monday morning, Stan Rosenfield said, “I have worked with Charlie Sheen for a long time and I care about him very much. However, at this time, I’m unable to work effectively as his publicist and have respectfully resigned.”

The statement was issued immediately following an interview Sheen did with TMZ.com that was streamed live on their website.