The crash occurred on the eastbound lanes in Woodland Hills near the Winnetka Avenue exit.
Authorities say an 18-year-old was ejected from vehicle and pronounced dead at the scene.
Los Angeles County Fire Department personnel were called to the scene of the single vehicle crash at approximately 5:34 p.m.
Neither man was wearing a seat belt, the CHP said.
Three people were killed and two others injured Friday in a rollover accident, authorities said.
A 17-year-old boy from San Fernando was killed Sunday in a two-vehicle crash on the Foothill (210) Freeway in Tujunga.
Authorities Friday were investigating a fatal traffic collision involving two vehicles in Santa Ana.
A patient was trapped Monday after a rollover accident involving an ambulance.
The San Bernardino Sun reports several people were ejected from the vehicle.
Firefighter Jacob Gregoire, a 12-year veteran, was handcuffed on camera.
Seven children were injured in a rollover crash on the 10 Freeway, according to authorities.
A female motorist died Sunday in a SUV rollover crash on the 405 Freeway.
Five people were killed and two critically injured — all members of a Southern California family — in an early-morning crash near the Utah border Saturday morning.
A 32-year-old woman was killed in a rollover crash in Watts Saturday evening.
Five people were injured — two children critically — when the SUV they were riding in overturned on Interstate 15 in Murrieta, the California Highway Patrol said Sunday.