The victim was pronounced dead at the scene.
The closure will take place Saturday from 1 a.m. to 6 a.m. and Sunday from midnight to 6 a.m. Monday from Getty Center Drive to Santa Monica Boulevard, Metro said.
Los Angeles mayor Eric Garcetti gave his inaugural State of the City address on Thursday, discussing challenges for the city as well as potential solutions.
Crews Tuesday were battling a fire near the southbound side of the 405 Freeway at Roscoe Boulevard.
A motorist was arrested and another rushed to a hospital following a fiery crash in LA Friday night which temporarily closed the southbound 405 Freeway.
The southbound lanes of the 405 Freeway through the Sepulveda Pass will be closed Wednesday and Thursday nights.
The northbound 405 Freeway at Hawthorne Boulevard in Redondo Beach was shut down for a short time Tuesday night while police searched for a possible gunman.
Overnight closures in the West Los Angeles area will make driving this weekend a bit more complicated.
A 52-year-old man was fatally struck by a vehicle Monday night after he attempted to cross the southbound 405 Freeway in Irvine.
A pedestrian was fatally struck Wednesday morning on the northbound 405 Freeway through the Sepulveda Pass.
Authorities said a pedestrian was fatally struck by at least one vehicle Saturday on the northbound San Diego (405) Freeway in Westchester.
Crews wrapped up an 80-hour closure of the northbound 405 Freeway through the Sepulveda Pass Tuesday morning.
Crews Monday night were wrapping up the construction work, dubbed “Jamzilla,” that’s partially shut down the northbound 405 Freeway.
Many drivers were heeding warnings to steer clear of the Sepulveda Pass this Presidents Day weekend.
Ramp and lane closures expected to last until early Tuesday began late Friday night on Interstate 405 as the Los Angeles region undergoes another major freeway shutdown with a frightening nickname.