UCLA-Developed Mouthwash A ‘Smart Bomb’ Against Cavities?

WESTWOOD (CBS) — A mouthwash concocted by a UCLA microbiologist may render cavities and tooth decay a thing of the past.

The innovation developed by Wenyuan Shi, chairman of the UCLA School of Dentistry’s oral biology section, acts as a sort of “smart bomb” against harmful bacteria like, S. mutans, a main cause of cavities and tooth decay.

wenyun shi1 UCLA Developed Mouthwash A Smart Bomb Against Cavities?

Wenyuan Shi (credit: UCLA)

“With this new antimicrobial technology, we have the prospect of actually wiping out tooth decay in our lifetime,” he said.

A successful clinical study involving a dozen people found that those who rinsed with the UCLA-developed mouthwash just once over a four-day testing period experienced a near-complete elimination of the S. mutans bacteria.

Shi has been working on the innovation for over a decade with support from Colgate-Palmolive and a company he founded, C3-Jian Inc.

He said the findings may lay the groundwork for developing other target-specific anti-microbials to combat other diseases.

In a news release issued by the school, UCLA School of Dentistry, Dean, Dr. No-Hee Park is quoted as saying, “the work conducted by Dr. Shi’s laboratory will transform the concept of targeted antimicrobial therapy into reality.

“We are proud that UCLA will become known as the birthplace of this significant treatment innovation.”

More extensive clinical trials on the mouthwash may begin as early as March 2012.

(©2011 CBS Local Media, a division of CBS Radio Inc. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed. Wire services contributed to this report.)

  • alg

    great for kids, but what about all the rest of us? Is there anything that can be done for older americans without dental insurance. Of course there is no company that will provide insurance on anyone over 65, or no other insurance. period.
    Will this work for the rest of us.???
    I’m going to contact him, and the UCLA SCHOOL OF DENTISTRY , find out, and will report back, unless someone from that area can comment first. very good news though. Our technology is unbelievable. Every day something new happens. Wish I were much younger.

    • Bridget

      Please find out whether the substance includes Xylitol–a sugar substitute that also eradicates tooth decay, but is already on the market.

    • Mike

      Yes – you could rinse with colloidal silver.

      • mustBtheSwineFlu
      • Dean

        If you are going to post a link, post both sides on colloidal silver, actually now the next generation is ionic silver or silver hydrosol

        “Common substances like table salt and aspirin are harmless with normal use, but excessive intake can become toxic and even life-threatening. With normal responsible usage, silver supplements are entirely harmless to humans.”

        Says Jeffrey Blumer, M.D., Ph.D., director of the Center for Drug Research, the world’s largest clinical research center for pediatric drugs, and former director of the Greater Cleveland Poison Control Center:

        The Environmental Protection Agency’s Poison Control Center reports no toxicity listing for colloidal silver and considers it harmless in any concentration. Colloidal silver is the safest and best all around natural antibiotic germ fighter

    • Ebola

      There is always a door knob and a string

    • TH3M0N5T3R

      You had 65+ years to build a nest egg. Why didn’t you? You spent, and borrowed, and spent, and borrowed, and now you want the rest of us to pay for your generations’ binge.

      Cry me a river. You want all sorts of “senior discounts” and “senior benefits” and “senior protections”. The way I see it, you’ve got more experience, so you shouldn’t be scammed so easily. You’ve had more time to save and learn to budget, but you didn’t. The working generation is already paying too much for your folly.

      • RobertT


        Not to mention the retirement age was 65 and the avg lefe expectancy was 67. now the retirement age is 65 and the avg life expectancy is 78.1 years. Fewer people paying in, a period of receipt six times what it was= FAIL.

      • Syrin

        Preach it bro. The “me generation” can’t suck away their kids’ and grandkids’ future fast enough.

        By the way. does anyone here know ANYONE with dental insurance?

      • baseballguy2001

        TH3 is right on the money. Who says it’s up to us younger folks to finance the older folks who didn’t save and invest for their “Golden Years”. The younger crowd sick of it and we intend change things.

      • albert8184

        And you know, you young people are right. I was saying this to my generation 30 years ago, and they laughed like hyenas at the thought that their stupidity would ever come back to haunt them.

        And I told them that the next big social fracture to come would be the young against the old, and they laughed at me. Thirty years ago I said this, I swear to God, and now it is starting to happen.

      • JJtheTraveler

        I agree completely. Lets put more big spenders in office. lets reelect obama so he can spend more of your money. I just love lib big spenders.

      • Cliff James

        What a moronic statement, made by the ME generation. You have not worked 25-30 years, then have the company go bankrupt and along with it, your retirement. Or lost your 401K, keough plan, or stock investments in the two crashes in his lifetime. You have not experienced medicare and medicade, or the need for supplemental insurance to cover what they do not, and mostly, you do not have a clue what this mans life has been like, so have no bisis for your comments that would relate to any facts. Yet, your ME generation, still lives with mom and dad, or suck off the welfare system, or complain and whine about anything and everything. Meanwhile, real life, and real issues go on. What suprises me is that this issue will help everyone, and you attempt to turn him into a moocher, and you a victim, as well as your fellow posters. you just prove my point.

      • thoughtful blogger

        What a self-righteous pig you are, THMON5T3R. You know nothing about anyone else’s situation. What about people who are laid off from a job, or have a car accident and get hurt, or have a crisis in the family that sucks up a life’s savings in days or weeks? This can happen to people who are victims of wildfires, floods, hurricanes, cancer or heart attack patients, people hit by a drunk driver who is uninsured, to name just a few examples.

      • baseballguy2001

        @Cliff and others — the meaning of ‘save and invest’ is exactly for the bad situations you describe. My generation, Gen X, we are stuck with the bills of our older brothers and sisters, and our parents, and we have to try and save and invest for our Golden Years. The rapid expansion of the welfare state costs money, truckloads of money, and paying high taxes to pay for the welfare state cuts into our saving. The young kids behind us, the 20 somethings, they may be more self indulgent then the older generations from the 60’s or 70’s. Don’t lecture us for being mean, we are trying to save the country.

      • Tom

        Excuse me man but I’ve paid into SS since I was 12 some 56 years, paid taxes up the wazoo my whole working life so YOU could get an education…so bleep you…ahole

      • Mom of four

        We did…. in 2001 our nest egg for 20 years hence was worth over $500K. Twelve years later? $100K. That’ll pay our way for how long? We did save, we didn’t borrow. Yet as I look to next year when my husband turns 65…, we can forget about retirement. We haven’t had a vacation in the last 5 years trying to watch our dollars as we get closer and closer to retirement while our children take cruises and extensive vacations. So cry me a river you little snot! You have the next 30 years to save. I hope to God you don’t lose it like we did. We were the working generation and we sure didn’t folly. I see too many 50+ losing their jobs just as they get the kids college paid off and can’t find a job because younger is cheaper. So give it a rest until you know what you are talking about. Idiot!

      • baseballguy2001

        @Tom — Congratulations! You and I both have been working since before were were teens! You are older than me so your savings and investments outside of Social Security should be even larger than mine since you’ve had more time to put it away. You did set some $$ aside didn’t you? I’m not counting on Uncle Sam at all. Some of us decided years ago to exercise PERSONAL RESPONSIBILITY in an effort to take care of ourselves, and not rely on others. No, I can’t recommend an investment guy, I learned the hard way myself. I can recommend a good mechanic. I’ve been driving the same 1982 Jeep Wrangler I got in college and he keeps it going for me.

      • baseballguy2001

        @Mom – I’m very sorry you lost 400 Grand of your retirement. However, I am not responsible. Did either you or Pop wonder what was happening and try and stop the losses after the first 100 Grand was gone? Saving is not like the latest gadget from Ronco, you can’t just “set it and forget it”. Market conditions change, businesses fail, (they used to anyway, before govt bailouts) other companies thrive. Oh, and if it’s a medical thing, trust me, I know all about it. Both my folks passed away after long fights with Cancer. My sisters didn’t cough up a dime to pay for the folks medical bills, they, like most people don’t have any savings. Invest the last 100K wisely, you might be ok.

      • alg

        baseball guy, and all those related to his philosophy – It’s so easy to get distracted when trying to keep on the subject on TEETH, and the PRESERVATION forthwith.
        As for you guy, please do me a favor. Next time you’re at a ballgame., please go stand between the pitcher and the hitter. If you stand there long enough, the pitch will hit you in the head. When you wake up, you just might have more sense than you do now.

      • RSchimes123

        Thanks for hitting the nail on the head, they did get derailed.

      • Lex

        ID10T – ObamaCare means you take my money that I worked for, for my family (and theres not much left over from each paycheck just so you know) and gives it to someone else. I dont like that. I am not comlplaining. I just want to be left alone with my own family and money. I dont want anyone to pay my bills. And I will pay my own way. Everyone else should do the same. Preparation from an early age (school) and hard work will get you there.

      • biffula

        Hey Tom, if all you planned on was s.s. for your retirement, then that was your first mistake. Politicians have been warning us for DECADES that it was on a path of destruction. You old fools placed all your faith in the federal govt. instead of taking care of yourselves. Sorry, but look at all the Flea Party, aka occupy, fools, you think those dolts are gonna know how to run things?

      • Kampfhund

        I’ve never read such a blatantly stupid and hostile comment, themonster. And what a troll comment it is. You win the award for ‘old person troll’ for the day, sir.

      • i ndianwithoutacasino

        i have dental insurance….what’s the problem bub?

      • Amazed One


        Your awsome display of a total lack of compasion and understanding about life and its many turns that affect people shows your total pompus selfish attitude!!!

        Good luck with that in life, I imagine it will serve you well as you leave your path of bodies and destroyed relationships behind you.

      • PFWAG

        Very few people pay more into Social Security than they will get out.

        Social security is nothing more than an inter-generational income transfer Ponzi scheme.

        It was flawed from its inception. The first benefit check for $22.54, was paid to Ida May Fuller in 1940. Ms Fuller had paid a grand total of $49.50 in Social Security taxes into the system prior to her retirement. She ended up living to be 90 and collected $22,889 in benefits. Such large returns are only enabled by the Ponzi-like features of the system. When Ms Fuller received her first Social Security check in 1940, there were 42 workers paying into the system for each retiree. Now there are just over three with that number soon falling to about 2.5 as all the baby-boomers retire.

      • alg

        I’ve worked from the time I was 10 years old, paying into the system. I still have not gotten back what I paid into it. I have all the records. In about 15 years I should get back what I paid into it. I doubt seriously if I will live that long.
        What about all the people who work and die before 62(legal retirement age)?
        Then there are those that are killed in all kind of accidents that have paid into the system. They never see a dime of that money. Where does it go?
        The problem with SOC. SEC. is that the GENERAL FUND, and the congress have BORROWED billions from that fund, and HAVEN’T PAID IT BACK.
        The same thing with the POST OFFICE. It’s outrageous what they have to do with their funds. Check it out, you won’t believe what’s going on.

      • Ted

        Your comments our out of line. To make such a blantant remark is irresponsible. The old saying applie here: “Until you have walked in someone else’s shows, you know not what it is like”. Have some compassion here.

        I bet you also believe there is a real government and Lawful Tender as well.

        Maybe you should study and learn real history,as t appears you got your schooling in the “PUBLIC FOOL SYSTEM”.

      • notpayingforyou

        monster is absolutely right. its not from “lack of compassion” either. simply calling out you old basterds that, through your utter disregard for anyone but yourselves, you have successfully robbed us blind. i cant believe any of you baby boomers have the balls to tell us WERE entitled when our grandchildren will be paying off YOUR debt.

      • LiliQ

        what a moron. Did your elementary teachers tell you that money was invented by God?

        How long do you believe that people have relied on money anyway?

    • jo

      Me and my kids have never had dental insurance. Had to pay for our dental work out of our own pockets. Why do you need insurance? Just pay for it yourself.

      • anita daeoph

        we go to Mexico and see an oral surgen; he is top of the line. The” adobe and chicken wire” did wonders for my brothers’ teeth and 35% of what the american dentist was going to charge and half the time.

    • Dr. Rober Jacobson

      So many others have done the same thing, this is not news, read below:
      According to Dr. Ron Leavitt of BYU University, a quality colloidal silver may serve as a suitable antibiotic alternative.”The data suggests that with the low toxicity associated with colloidal silver, in general, and the broad spectrum of antimicrobial activity of this colloidal silver preparation, this preparation may be effectively used as an alternative to antibiotics.”

      The original study tested ASAP colloidal silver against tetracyclines, fluorinated quinolones (Ofloxacin), the penicillins, the cephalosporins (Cefaperazone) and the macrolides (Erythromycin). Among the microbes tested were streptococcuses, pneumonia, E. coli, salmonella, and shigella.

      See full article here:

      How come this guy isn’t on TV and a celebrity now too?
      Actually, this dates back to 100 years ago

    • LAguy

      There is nothing in the article that indicates that it works only for kids (merely the statement that cavities are the bane of childhood existence). If it wipes out the bacteria that causes cavities it will work for everyone. This is great news and I do wish it had been developed before I developed a mouth full of fillings. As far as your other dental care — there are places that provide free or nearly free dental care — our dental schools. UCLA has a dental clinic where students work on patients under the very careful supervision of dental professors. I have sent a number of clients there who cant afford dental care and they report really good results. If you don’t live in LA look into university dental programs near you. Good luck.

      • Jubal

        Strep. mutans was identified in the 60’s and a specific antibiotic mouthwash developed then. The AMA and the Dental industry, with backing from the FDA shut the researchers down big time. How much money does a dentist make off of someone that has no caries? As much as a MD makes off of a healthy person.

      • Stan

        Dental industry lobbyist will never let this drug see the light of day. My guess is that the Mouthwash was patented..Next step is the Dental Industry lawers will buy the patent, and then say that after further reaearch the intial analysis was wrong.

      • Ben

        It has been developed before. I remember reading about a similar treatment around a decade ago. The problem is that it was impossible to find enough adults who qualified for the clinical trials, due to the fact that just about everyone gets cavities in childhood, so it could never get cleared for use in human mouths.

    • beedogs

      Hm, if you morons would stop opposing “Obamacare”, maybe you’d get some dental work paid for.

      You can’t have your cake and eat it (with your dentures), too.

      • David Maxwell

        Please show me the section number in ObamaCare that covers dental care you egg sucking snit. Hint, it doesn’t exist. I can tell you what section it is not; that would be section 713 that provides funds to cure child molesters.

      • Joanna

        Sweetie – there ain’t NO FREE LUNCH. Somebody has to pay for it. What makes you think that I want to pay for mine and YOURS too?

      • Justin Case

        Typical parasite Lib viewpoint

      • http://imallset.wordpress.com jeff22192

        Great way to start an argument…People oppose Obamacare because they don’t feel as though they should have to pay for the sick, lame and lazy.

      • Il Bui

        What ARE you babbling on about now?

      • Nrgmanager

        beedogs, the day you pay for my dental insurance is the day I will oppose “Obamacare”….get it?? Someone has to pay for it…you and the rest of your “what’s in it for me” morons have run the cupboard bare. I along with the rest of the taxpaying citizens are going to send you idiots a very clear message Nov. 2012….if you want it…pay for it. If you can’t pay for it, don’t get it…too back our union backed-education system doesn’t teach these kind of economics anymore.

      • Nico Henstock

        Are you kidding? Obamacare will make sure that less and less people will have more expensiv, worse quality and less available care. Check out the UK, a “free” healthcare paradise. Health care is being rationed, hospitals can’t afford to provide medicine, patients are told to bring their own aspirin, bandages etc., and for orthodontics there is a lottery system. Your post about having some dental work paid for shows the lack of thought on your part. Somebody is paying for it, and when you run out of other people’s money then it’s over, even if you’re willing to pay for it yourself. That’s when you go to Switzerland (if you’re in Europe) or in the US (if you’re in Canada), that is, if you can afford it and if you haven’t died yet for lack of care. Just ask anyone living in a socialized-medicine country.

      • Lavenderhillmob

        People don’t oppose Obamacare because they don’t want to pay for someone elses service. They oppose it because they’re racists, remember?

      • alg

        lavenerhillmob – I thought about your comment for a while, and said to myself ” what kind of racist is that?” You must be talking about the rich republican extreme white race that hates all the other races that are POOR, and can’t afford healthcare.
        Then I thought no, it must be ALL the rich races that hate the POOR, INCLUDING their relatives and friends who are poor. I agreed with myself that there are people like that. People who have billions of dollars tucked away, and being miserly with others. Not sharing, “self-interest” selfish, uncaring, no feelings whatsoever for anyone but themselves. They go to such an extreme that they don’t care if the country of the UNITED STATES OF AMERICA goes down the tubes. Those people will just move to another country, and do the same thing there. and so on, and so on, etc.
        I predicted two years ago there would be a revolution. Not the protests you see in the streets now. I don’t really know what kind, but when it happens I will know, and so will you.

    • Sharon

      I am well over 65 and have private insurance. Of course, it does not pay much but my husband provides it to our employees so we have it.

    • toothman

      wa wa wa – get out of the trailer and buy a toothbrush….

    • tek

      I am familiar with the technology and yes it works for adults too. The “smart bomb” targets specific bacteria, whether those bacteria are in a child or an adult has no affect on the action of the “smart bomb”.

  • Darrell Nelson

    i hope this really work and very soon… went to western dental on western & venice and those kids go thru some excruating pain in there, and even i went thru some painful treatment from the old fart that pulled my tooth. i still have one that is a stump an looks like i will die with it there. good work ucla.

  • http://babybottletoothdecay.wordpress.com thomasandy

    i hope this really work and very soon…YOU ARE RIGHT about that it is a smart bomb against tooth decay.it is dedicated to improving the oral health of the people. great for children. Eating a well-balanced diet and those that contain high levels of carbohydrates will help you battle tooth decay. nice post.

    • Jeremy

      Carbohydrates are what strep mutans turns into acid which causes cavities. Eliminating carbs eliminates the cavities.

    • Dave Hart

      slow down a bit though — is that really enough to time to determine what long term effects absorption of whatever chemicals this is will arise? The membranes in your mouth are one of the easiest ways to absorb external molecules, so let’s be cautious on getting everyone to use it! Especially an entire generation of youth!

      • hooray for everything

        Yeah, I was thinking that too. But then again they’ve been promoting flouride for three generations and that’s pure poison(read the back of your toothpaste)

    • beedogs

      Really? Your advice to people is to “carb up”?

      So they’ll all be 500 pound land-whales but their teeth will be fine?

      • Nico Henstock

        Great point! I’d rather have a cavity that can be filled with a compound that looks like my tooth than be fat.

  • Jeff Little

    Eh? Where the hell do you get that?

  • Brad Skidmore

    The technology to target specific bacteria is at least 50 years old… Look into Bacteriophages http://en.wikipedia.org/wiki/Bacteriophage

    Phages are natural viruses which have coexisted with every type of bacteria… In other words, nature already has a defense against bacteria to keep them in check. One specific type of phage for every strain of bacteria… as bacteria evolves so do the phage.

    • RSmile

      Here’s some even better news for all of you: Dental caries (lay term = cavities) are PREVENTABLE. Those strep mutans bacteria need carbs to survive. They eat a carb and produce acid. It’s the acid that decays your teeth. Your body’s natural defenses send bases to the mouth to neutralize the acid. If you take a 90 minute rest from carbs after you’ve eaten a meal, your acid level will never rise high enough to start the decay process. It’s all about diet and timing. Additionally, dental caries is a contagious disease- the mother usually innoculates her children with her strain of bacteria. If she has a lot of dental disease, her bacteria are stronger, thus the child is at higher risk. Moms-to-be: take care of your cavities now! Watch what and how often your kids eat (a bag of Cheerios is just as bad as a baby bottle at night). With love and concern for our nation’s smiles, from a military dentist.

      • Flossie

        You are exactly right about the carbs/acid connection. With the proper diet caries is nearly nonexistent. I have a bad feeling about this new “innoculation.” What are the chances improper or irresponsible use will lead to stronger strains of S. mutans, as misuse of antibiotics has done?

  • Vicky Bevis

    I am thrilled. Too late for me & older people, but wonderful for the upcoming generation. It’s about time someone invented a cure for something instead of just “marginally improving” common conditions.

    Nothing discovered since Salk/Sabin changed Polio way back in the 1950’s & how long have we been giving to “Jerry’s Kids” w/o a cure.

    (Retired Nurse)

    • Dave Hart

      It’s not a cure.. bacteria come and go. it’s just supposedly an effective treatment. One that hasn’t gone through proper trials. I would trust something like this if people were using it for about 20 years, so that we could see what effects it has on development of children. Cavities aren’t a big deal when you brush every day (and this isn’t a replacement for that — read carefully), I can wait.

      • alg

        I am astounded by the response to this article.
        When I read about kids going to the dentist, I can only wonder what happened to our THREE SETS OF TEETH?
        I think it’s three, maybe two, I forget. I’m getting too old to remember.
        Anyway, I never went to a dentist until I was around 20 to have a wisdom tooth removed. I still have the other one.
        I can’t wait until the STEM CELL research makes regrowing the teeth I’ve lost possible.

    • JustSayNoNow

      You are right! There have not been enough major breakthroughs – in spite of all of the billions spent on research. Yes… there have been some advancements, but no ‘cures’. This is a big one from UCLA, but what about the big killers… cancer, renal disease, Lymphoma,….on and on.

      • Dave Hart

        I would argue that we are not allocating nearly enough on science.. hopefully when our government gets serious about fiscal responsibility, they will also start evaluating the priorities that dictate spending. And hopefully they will stop allowing corporate interests from influencing those decisions. There is no point to debating when our will is never respected by our elected public servants, who seem to think their high salaries and ability to trade on inside information are perks of being royalty.. We surely pay them too much for what we get.

      • zzz

        They’ve been testing it on me for 20 years.

        Not only have I bright and beautiful teeth, but I have acquired Telekinesis, Psychokinesis, and Pyrokinesis.

        Can you feel me in your head, right now?

      • hooray for everything

        I would argue that most of the monies we alocate to science don’t go to science at all. I would say it goes to pay some committee who will study about which science we should have spent the money on that was spent on the committee.

      • John Davies

        Two years ago I had my gall bladder out. They made five small incisions thanks to the MRI and CAT scans they performed. The scars are almost invisible now. Precision like that wasn’t available ten years ago.

  • mommaroo

    Now all we need is something to cause extracted teeth to grow back!

    • alg

      MOMMAROO – be careful what you wish for.!!
      Experimentation is ongoing to do just that. STEM CELL research for regenerating teeth is at the top of the list. Hopefully the government and the ADA & the FDA won’t interfere with the testing., etc.
      We are on the verge on new technology in every field of science.
      Dentistry is only one of them.

    • comment submitter

      I hear Obamacare is suppost to fix that with the doughnut hole bill. Oh wait that was canpaign promise. my bad

  • Me

    It’ll never pass FDA, it would put way to many out of business…

    Bio-Engineers have made anti-plaq creating mouth germs a few times over the last 30years… They never get out of FDA testing…

    • hooray for everything

      Yeah and lets see if 4 out of 5 dentists reccommend this product to their patients…………

  • bikermailman

    I just wonder if it will have the same effect as other antibiotics: a buildup of resistance

  • Daisy

    I’d stay away from Dentist Conventions if I were him; he would be ‘disappeared’.

  • David Moore

    What will I do with all this dental floss?

  • Ed

    IT WILL NEVER HAPPEN…too much is being invested in depopulation programs like putting fluoride in the water as an excuse to combat cavities. This news will probably be talked about today, but never again via a media-induced sleep.

    • Dave Hart

      You’re assuming that this new “breakthrough” is safe..

    • hooray for everything

      No, this IS one of those “investments”

  • sueinmi

    Quick…invest in Mountain Dew stock.

    • Daisy

      LoL! Perfect !!

    • hooray for everything

      ……and put me down for a thousand shares of Skittles

  • Skeptical

    Sounds great but what of long term side effects? Everything causes cancer these days. I hope it works out. Tooth decay and bacteria in the mouth causes all kinds of sickness and eliminating that will create healthier people.

    • Dave Hart

      I agree.. even so, what’s wrong with brushing and flossing? Yeah it’s annoying but not that big of a deal. I haven’t had a cavity in many years and all I do is brush two or three times daily.

      • Potsie Webber

        Two or three times a day!!!!
        I’ll just take the side effects.

        Is UCLA working on the Perma-bath project yet; I’m about tired of having to take showers.

    • LiliQ

      To Potsie and the Perma-Bath, not UCLA but private enterprise just came up with the water repellant spray. Apparently will hit the market in the next year ot two. Just spray under the armpits and relevant areaa.

  • Rachael

    This is the right way to combat tooth decay. While it will take a while to get approved, I was able to get similar results by switching my toothpaste and mouthwash to xylitol. I used the regular detergent + fluoride toothpastes like Crest for years and had at least 2 cavities per year. Then I became concerned about the health effects, so I switched to fluoride-free toothpaste made from xylitol. Much to my surprise, I have been cavity free for 5 years (with no changes to diet, and I still eat chocolate every day). The bacteria that case tooth decay can’t grow in the presence of the xylitol, and you won’t get cavities.

  • Mitchell Kent

    Let em guess, its a mouthwash (like washes weve had for years) yet for some reason it will need to be administered as a “therepy” by a dentist, on a reocurring basis, and will run us $500 to $750 a visit…? right? never mind it a mouthwash that should be bought for 6 bucks over the counter like any other wash… this will do away with companies putting out mouthwashes… so of course it will need to be terribly expensive.

  • Original Killshot

    Xylitol is a plant sugar that kills s mutans and has been around for years as a toothpaste, mouthwash, and gum. This is not new at all. Regular use of xylitol does all this, is cheap, and is NOT patentable. So, UCLA, this is nonsense.

  • Mitchell Kent

    The mouthwash? or just my common sense based on experience? why are there tiny little pills that cost $120 a piece? why is the price of medicine so out of control that we have to leverage our lives away and pay huge sums of money for “insurance” to pay these exorbitant costs of medicine?

    I will eat my words when this product comes out and is on store shelves for your average mouthwash price… IF it does. Im betting it will be an expensive proceedure at the dentist.

    • Jeremy

      R&D costs money. You devote 10 years of your life to develop a new medicine after maybe spending 15 years before that on a medicine that did not work and hand it out for free.


    As a dentist for many years I’ve been recommending for all my patients an oral probiotic that’s available at all Walgreens in their mouthwash section, called TheraBreath Probiotics. It uses a blend of 2 oral probiotics (K12 + M18) to prevent tooth decay, bad breath, periodontal disease, as well as ear aches – and it’s all natural, so no side effects Tons of research at http://www.therabreath.com/probiotics/.

  • Diego Roswell

    We will never see a product like this. Vaccines for tooth decay bacteria have been around for decades but to allow them on them market would hurt the dental hygiene products industry. Wake up people, lobbyists in Washington decide what you get, not science.

  • John

    The FDA will never approve this. Anything that attempts to cure health conditions will never be approved, they’d rather us pay forever to keep conditions under control….but never cure them.

    The Republicans for sure will be against it.

    • Albert8184

      So John, are the Democrats complaining much about big goverenment agencies like the FDA that collude with corporations to rape the Ameircan people?

      I didn’t think so. Shut up and go away.

    • jo

      Republicans? Well, that sure took me for a surprise. I guess you’re for Obamacare, where old folks and disabled children will be on the bottom of the list for healthcare, since they are not as “worthy”. Just wait until you can’t pray in a hospital and then let’s hear you spew about republicans.

  • Steve

    All we need now is a cure for baldness.

  • Fang Wang

    Another Chinese fraud… a year from now there will be another article about how the field is shocked, SHOCKED! that such a well respected scientist would defraud the world.

    • Dillon

      You are not wanted here Mr. Mexican.

  • Tracey12

    You all have missed the primary point! Yes, this is a great invention that will affect many industries particularly your family dentist and future dentists, therefore, the chance of this patent to be bought and locked up is very great. Will someone rush in with billions and pay off the developers to keep many dentists and associated companies alive?

    • Potsie Webber

      The answer is yes; an I hear we’re getting ready to bail out the wagon wheel and the telegraph industies as well, just waiting on a committee.

  • Tracey12

    By the way, Obama is the worst president in recorded history. Do I hear an “Amen”?
    Be sure to name your Thanksgiving Turkey after a goofy member of Congress, or this admin.

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